Local anesthetic amide local anesthetic Bupivacaine CAS:2180-92-9
Quick Detail:
Product Name |
Bupivacaine |
CAS No. |
2180-92-9 |
MF |
C18H28N2O. ClH |
EINECS No. |
218-553-3 |
MW |
324.89 |
Purity |
99% |
Appearance |
White powder |
Package |
Foil bag or tin |
Structure:
Usage: Bupivacaine hydrochloride USP is 2-Piperidinecarboxamide, 1-butyl-N-(2,6-dimethylphenyl)-, monohydrochloride, monohydrate, a white, odorless, crystalline powder that is freely soluble in 95 percent ethanol, soluble in water, and slightly soluble in chloroform or acetone.
Description:
Bupivacaine hcl injection, USP is available in sterile isotonic solution for injection via local infiltration, peripheral nerve block, and caudal and lumbar epidural blocks. Solution of Bupivacaine hydrochloride injection, USP may be autoclaved. Solution is clear and colorless.
Applications:
Bupivacaine is related chemically and pharmacologically to the aminoacyl local anesthetics. It is a homologue of mepivacaine and is chemically related to lidocaine. All three of these anesthetics contain an amide linkage between the aromatic nucleus and the amino. They differ in this respect from the procaine-type local anesthetics, which have an ester linkage.
Bupivacaine hydrochloride injection, USP - Sterile isotonic solution containing sodium chloride. The pH of the solution is adjusted to between 4 and 6.5 with sodium hydroxide or hydrochloric acid.
Bupivacaine is an anesthetic (numbing medicine) that blocks the nerve impulses that send pain signals to your brain.
Bupivacaine is used as a local (in only one area) anesthetic.
Bupivacaine is given as an epidural injection into the spinal column to produce numbness during labor, surgery, or certain medical procedures.
Bupivacaine is also used as an anesthetic for dental procedures.
Bupivacaine may also be used for purposes not listed in this medication guide.
COA:
Test Items |
Specification |
Test Results |
Appearance |
Fine, white, crystalline, odorless powder |
confirm |
Identification |
A\B\C in Pass |
confirm |
Solubility |
Very soluble in chloroform, soluble in Alcohol and Ether; insoluble in water |
confirm |
Melting point |
106~110 degree |
107.0~108.0 degree |
Related substance |
Not more than the reference solution 1.0% |
0.40% |
Heavy metals |
≤ 10ppm |
confirm |
Residue on ignition |
≤ 0.10% |
0.05% |
Loss on Drying |
≤ 1.0% |
0.20% |
Assay |
More Than 98.5 % |
99.40% |
Conclusion |
Confirms USP32 |